A balanced secondary structure predictor

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A Balanced Secondary Structure Predictor

Acknowledgement First of all, I would like to humbly express my profound gratitude to my supervisor Dr. Md Tamjidul Hoque for being so kind, enduring and at the same time vigilant in every aspect of my research and academic progress during the whole time I have been here at University of New Orleans. He has been tireless to explain every nuances again and again till I felt little uncomfortable ...

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A balanced secondary structure predictor.

Secondary structure (SS) refers to the local spatial organization of a polypeptide backbone atoms of a protein. Accurate prediction of SS can provide crucial features to form the next higher level of 3D structure of a protein accurately. SS has three different major components, helix (H), beta (E) and coil (C). Most of the SS predictors express imbalanced accuracies by claiming higher predictio...

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BaCelLo: a balanced subcellular localization predictor

MOTIVATION The knowledge of the subcellular localization of a protein is fundamental for elucidating its function. It is difficult to determine the subcellular location for eukaryotic cells with experimental high-throughput procedures. Computational procedures are then needed for annotating the subcellular location of proteins in large scale genomic projects. RESULTS BaCelLo is a predictor fo...

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Secondary Structure Effects on the Acidity of Histidine and Lysine-Based Peptides Model; A Theoretical Study

     In this study, the effect of the secondary structure of the protein on the acid strength of three structures of random (R), alpha helix (α) and beta sheet (b) were investigated theoretically. These structures are related to the cationic amino acids of histidine and lysine in the polypeptide chain of eight-glycine residue. Computational methods at the HF, B3LYP, X3LYP and M05-2X levels in t...

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Protein Secondary Structure Prediction: a Literature Review with Focus on Machine Learning Approaches

DNA sequence, containing all genetic traits is not a functional entity. Instead, it transfers to protein sequences by transcription and translation processes. This protein sequence takes on a 3D structure later, which is a functional unit and can manage biological interactions using the information encoded in DNA. Every life process one can figure is undertaken by proteins with specific functio...

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ژورنال

عنوان ژورنال: Journal of Theoretical Biology

سال: 2016

ISSN: 0022-5193

DOI: 10.1016/j.jtbi.2015.10.015